Health benefits of Lactobacillus Rhamnosus GG

Health benefits of Lactobacillus Rhamnosus GG
  • The human body contains 10–100 trillion bacteria.
  • Most of these bacteria live inside your gut, collectively known as microbiota. They play an important role in maintaining optimal health.
  • While there are many benefits to having a healthy balance of gut bacteria, an imbalance is linked to numerous diseases.

One of the most well-studied friendly bacteria is L. rhamnosus.



Brief Overview of Probiotics

  • Probiotics are live microorganisms that can offer health benefits when consumed
  • The health benefits of probiotics are beyond question, especially one of the most extensively studied probiotics, Lactobacillus rhamnosus GG.


Probiotics are bacteria and yeast that are good for you, especially the digestive system. 


  • Lactobacillus rhamnosus GG is one of the most widely used strains of probiotics. This is due to the vast body of scientific literature documenting its many benefits.


LGG was identified as a probiotic strain because of its resistance to acid and bile, good growth characteristics, and a capacity to adhere to the gut wall [1].



What is Lactobacillus rhamnosus GG


Lactobacillus rhamnosus GG (LGG) is a bacteria that was isolated from the gastrointestinal tract by research professors Sherwood Gorbach and Barry Goldwin hence the suffix letters GG. Since that time Lactobacillus rhamnosus GG has been one of the most widely studied probiotic strains and is used in a variety of commercially available probiotic supplements.


The ability to ‘stick’ to the intestinal cell wall prolongs the persistence of a probiotic in the intestine and allows it to exert its helpful effects longer. Health benefits for supplementing LGG include the prevention and treatment of gastro-intestinal infections and diarrhoea, promoting a healthy immune response, improving neural function, reducing inflammation, combating allergies and assisting weight loss [2].



Lactobacillus rhamnosus GG Benefits


Lactobacillus rhamnosus helps prevent diarrhoea and GI infections


Because of its excellent adhesion properties in the gut, LGG has been shown to help prevent and treat gastrointestinal infections and diarrhoea. LGG reduces the duration of diarrhoea in children [3], and significantly reduces the duration of diarrhoea symptoms in healthy adults taking antibiotics [4].



Administering probiotics containing LGG in hospitals has been shown to prevent patients contracting clostridium difficile infections [5]. Clostridium difficile is a bacterium that can infect the bowel and cause diarrhoea.



Lactobacillus rhamnosus for immunity


It is believed that probiotic microorganisms, especially LGG, have the ability to modulate the immune system. LGG increases the response of the body’s white blood cells, T-lymphocytes, to search out and destroy pathogens [6].


LGG reduces the pro-inflammatory chemicals produced in the body during an infection, and at the same time increases the anti-inflammatory response [7].


Lactobacillus rhamnosus LGG enhances the gut barrier defence against invading pathogens to help prevent infection [8].



Lactobacillus rhamnosus improves diabetes


Insulin resistance is the driving factor that leads to type II diabetes. Supplementing with Lactobacillus rhamnosus LGG has been shown to increase insulin sensitivity and decrease the risk of hypoglycaemia [9], where blood sugar levels fall to below normal levels.



Lactobacillus rhamnosus GG aids weight loss


Research tells us that there is a difference in gut bacteria between the overweight and those of healthy weight [10].


One study investigated the impact of Lactobacillus rhamnosus supplementation on weight loss and maintenance in obese women and found they were able to achieve sustainable weight loss [11].



Lactobacillus Rhamnosus GG helps with depression and anxiety


A growing body of literature has demonstrated bidirectional signalling between the brain and the gut microbiome [12], effectively meaning that the gut and the brain talk to one another. 


Studies have shown that Lactobacillus rhamnosus can positively help with symptoms of depression and anxiety [13].



Lactobacillus rhamnosus improves irritable bowel syndrome (IBS)


The role that probiotics play in relieving irritable bowel syndrome (IBS) has been demonstrated, but the mechanism remained unclear.


But supplementation with Lactobacillus rhamnosus GG was found to increase the production of serotonin in the gut [14]. Serotonin is a chemical that has a wide variety of functions in the human body. It is sometimes called the happy chemical, because it contributes to wellbeing and happiness.



Lactobacillus rhamnosus prevents eczema


A Lactobacillus rhamnosus supplement was found to prevent the development of eczema in a group of high risk children [15]. Even after ceasing the supplementation, children show a significantly less prevalence of eczema.



Lactobacillus rhamnosus improves dental health


Lactobacillus rhamnosus has been shown to improve dental health by keeping the numbers of Streptococcus mutans in check in the oral cavity [16]. Streptococcus mutans are a known cause of tooth decay.



Lactobacillus rhamnosus and candida


Candida is a yeast infection found in the mouth, intestinal tract and vagina. When it grows to excessive amounts in the gut, it can contribute to food sensitivities, leaky gut syndrome and a host of other negative physical and mental conditions.


Supplementing with Lactobacillus rhamnosus has been shown to significantly increase the effectiveness of pharmaceutical treatments of vaginal candidiasis [17].



Lactobacillus rhamnosus is beneficial during pregnancy


Establishment of a healthy gut microbiota at birth helps a newborn to develop a well-functioning immune system.


A prevalence of the species Bifidobacterium is associated with a healthy microbiota in newborn babies, and mothers that supplement Lactobacillus rhamnosus during pregnancy help the transfer and establishment of bifidobacteria in the gut of their babies [18].



Effective supplementation of Lactobacillus rhamnosus


It is always beneficial to digestive health to include probiotic foods within your diet, as these can help with nutrient absorption and support the immune system. Probiotic foods include kefir, fermented vegetables such as sauerkraut and kimchi, kombucha and yoghurt.



Harnessing the Health Benefits of Lactobacillus Rhamnosus GG


  • There are numerous scientific studies showcasing the many health benefits of Lactobacillus rhamnosus GG. Not only does it improve gut health, but it may also confer health benefits to other parts of the body.
  • However, we still need to learn so much about its mechanisms of action and its potential to address a broader range of health conditions.
  • At present, though, probiotic supplementation has been labeled as safe to use for healthy individuals. It is also well-tolerated by the body. Nonetheless, it is still possible to experience some die-off effects — especially as your body adjusts to changes in your gut microbiome.
  • The best way to avoid die-off issues is to go slow when first starting your supplementation. 



Dosage & Recommendations


  • L. rhamnosus probiotic supplements are easily purchasable. They can contain only L. rhamnosus species or these species combined with other probiotic bacteria.


A colony forming unit is used to quantify how many bacteria in a probiotic are capable of dividing and forming colonies. Generally, 5 billion colony forming units (CFU’s) per day for children and 10 billion/day for adults of Lactobacillus LGG are associated with more significant study outcomes [19].


  • For general health, 1 capsule containing at least 10 billion live bacteria is sufficient. To help prevent antibiotic-related diarrhea, take 2 capsules of L. rhamnosus GG daily providing 10 billion live bacteria or 1 capsule with over 20 billion live bacteria (52Trusted Source).
  • It is suggested to take the probiotic supplement a few hours after your antibiotic(s), then continue for at least one week after your course of antibiotics to help restore a healthy gut. Dosage guidelines have not been established for other uses of L. rhamnosus, but experts suggest that a similar daily dose may be appropriate.
  • Keep in mind that L. rhamnosus is sometimes added to dairy products — such as yogurts and milk — to boost their probiotic content and to cheeses to aid the ripening process.



Safety and Side Effects


  • L. rhamnosus products are generally safe and well tolerated with few side effects.In some cases, people may experience symptoms like stomach bloating or gas).
  • People with compromised immune systems — such as those with HIV, AIDS, or cancer — should avoid L. rhamnosus and other probiotics (or dairy products with added probiotics), as such supplements may cause an infection.
  • Likewise, if you’re taking drugs that may weaken your immune system — such as steroid drugs, cancer drugs, or medication for an organ transplant — you should avoid taking probiotics.
  • If you fall into these criteria or are concerned about side effects, consult with your medical provider before taking a probiotic supplement or dairy products with added probiotics.



Inessa Advanced Daily Biotic


Your gut holds the key to your optimal health and wellness,sSo help it find harmony with a clinical strength biotic. Inessa Advanced Daily Biotic delivers 10 billion CFU’s guaranteed to expiry date of Lactobacillus rhamnosus GG in advanced day release capsules proven to improve probiotic survival and delivery. 


Each delayed-release capsule bursts live Lactobacillus Rhamnosus GG bacteria and also contain the amino acid glutamine, which is a vital nutrient for the intestines to rebuild and repair. 


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Inessa Team

Our team pull together science-backed information to bring you up to date health and wellness insights.